Digital Brain Project

A $15M fund to open source neural data and model the human brain for science and medicine

Scaling Up

The research community answered our initial challenge with extraordinary enthusiasm, and we are proud to announce the scale-up of the Digital Brain Project to a total $15M USD. This will enable us to further accelerate open science by collecting and openly sharing neural data, develop foundational AI models of the human brain, and fast-track advances in neural disease diagnosis and treatment.

The Goal

How the human brain reasons, plans, and decides in complex tasks remains largely unknown. While brain responses to passive tasks start to be captured by modern AI models, how these neural activations govern intelligent behavior remains elusive. The Digital Brain Project aims to assemble the data necessary to build a functional model of the human brain during intelligent behavior.

The Approach

Neuroscientific teams across the world will collaborate to record the brain activity of participants while they perform interactive games inside brain scanners. The resulting dataset will be used to train a digital model of the human brain, which will then be validated against cognitive and reasoning benchmarks.

Naturalistic Interaction
Complex Games

Rich, interactive stimuli spanning visual, language, and auditory modalities—capturing reasoning, planning, and decision-making in action.

Train
Digital Brain
Digital Brain

Trained on 15k hours of
naturalistic brain activity
during interactive game play

Evaluate
Controlled Evaluation
Cognitive Benchmarks

Cognitive Science tasks probing perception, memory, attention, and executive function.

Reasoning Benchmarks

AI-benchmarkable tasks measuring planning, logic, and structured problem-solving.

Project Design

What Each Selected Team Does
1
Design Tasks

Design cognitive and reasoning tasks that probe planning, decision-making, and complex behavior.

2
Acquire Brain Data

Record a few subjects over many sessions, building dense individual brain maps of intelligent behavior.

3
Share Standardized Data

Contribute BIDS-formatted data to the central pool for cross-lab modeling and public release.

Deliverables
Public Data Dissemination

Deidentified dataset released under open source licensing for the global research community.

Co-authored Scientific Papers

Joint publications across teams advancing neuroscience, medicine, and AI.

Governance

Independent Scientific Committee
Review and Guide Awardee Selection and Project Execution
Executive Committee
Drive Project Execution
Rothschild Foundation Hospital
Coordinates project:
grant admin, legal & ethics, cross-lab standards, data governance
Université de Montréal
Advises project execution
External Teams · Parallel Data Acquisition
Team 1
Team 2
Team 3
Shared Data-Processing Pool
15,000 hours of standardized brain recordings
Dataset Release

Open Science & Impact

The full de-identified dataset will be released for open scientific research.

Brain Imaging Data Structure
Open Data
Reproducible Processing Pipelines

Improve Neuroscience

Better understanding. The project enables unprecedented in-silico experimentation. By aligning deep neural networks with brain data, we can predict high-resolution brain responses to novel stimuli without requiring new physical scans, recovering canonical neural responses and mapping the fine-grained topography of multisensory integration.

Help Medicine

Foundation for tomorrow's healthcare. Modeling the healthy human brain serves as a critical foundation for the future of neurological and psychiatric healthcare. This paves the way for integrating neuro-developmental trajectories and clinical pathology to capture the full diversity of the global population and better understand brain disorders.

Guide AI

Efficient architectures of intelligence. The representational alignment between deep neural networks and the primate brain helps identify the most efficient architectures of intelligence. AI foundation models help decode the brain, while insights from human brain data inform the design of more robust, human-like artificial intelligence.

Meet the Current Awardees

We're thrilled to welcome the following teams as the inaugural cohort to the Digital Brain Project, contributing world-class expertise in neuroscience, brain imaging, and cognitive research.

D. Bavelier
Daphne Bavelier
U. of Geneva
Switzerland
V. Borghesani
Valentina Borghesani
U. of Geneva
Switzerland
S. Cash
Sydney Cash
Mass. General Hospital & Harvard Medical School
USA
J. Diedrichsen
Jörn Diedrichsen
Western University
Canada
A. Ivanova
Anna Ivanova
Georgia Tech
USA
N. Kriegeskorte
Nikolaus Kriegeskorte
Columbia University
USA
S. Nastase
Sam Nastase
University of Southern California
USA
C. Pallier
Christophe Pallier
Neurospin, INSERM-CEA
France
M. Tomov
Momchil Tomov
Boston College
USA

Contributing Labs

Pierre Bourdillon
Pierre Bourdillon
TITAN
Translational Innovations and Technologies in Artificial Intelligence and Neuroscience
Hôpital Fondation Adolphe de Rothschild
France
Lune Bellec
Lune Bellec
Courtois Neuromod
Université de Montréal
Canada